Mouse MMP-8 Protein (pro form) (MMP-MM108)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Phe21-Ser465

Catalog: MMP-MM108

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Product Description Recombinant Mouse MMP-8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe21-Ser465.

Product Background

Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.

Product Category

Recombinant Protein

Target

MMP-8
Synonyms MMP-8; PMNL-CL; CLG1; MMP8; Collagenase 2; PMNL-CL; HNC

Gene/Protein ID

O70138

Species

Mouse

Exact Sequence

Phe21-Ser465
Molecular Weight The protein has a predicted MW of 51.9 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 50mM Tris, 10mM CaCl2, 150mM NaCl (pH 7.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Mouse MMP-8 is greater than 95% as determined by SEC-HPLC.
Mouse MMP-8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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