Mouse Neuropilin-2 Protein (NRP-MM102)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gln23-Leu859

Catalog: NRP-MM102

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Product Description Recombinant Mouse Neuropilin-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Leu859.

Product Background

 Neuropilins (NRPs) are single transmembrane receptors with short cytoplasmic tails and are dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are known to be important in angiogenesis, lymphangiogenesis, and axon guidance. The Neuropilin-family consists of two members, Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2). NRP2 is important for migration, antigen presentation, phagocytosis and cell-cell contact within the immune system. Additionally, posttranslational NRP2 modifications like polysialylation are crucial for the function of some immune cells.

Product Category

 Recombinant Protein

Target

 Neuropilin-2
Synonyms Neuropilin-2; NRP2; VEGF165R2; NP2; NPN2; PRO2714

Gene/Protein ID

 NP_001070871.1

Species

 Mouse

Exact Sequence

 Gln23-Leu859
Molecular Weight The protein has a predicted MW of 95.3 kDa. Due to glycosylation, the protein migrates to 110-116 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse Neuropilin-2 is greater than 95% as determined by SEC-HPLC.
Mouse Neuropilin-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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