Mouse NOGOR Protein (NOG-MM101)
Catalog: NOG-MM101
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| Product Description | Recombinant Mouse NOGOR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Ser447. |
Product Background |
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes. |
Product Category |
Recombinant Protein |
Target |
NOGOR |
| Synonyms | Nogo receptor; RTN4R; NOGOR; NgR1; Nogo-66 receptor; NGR |
Gene/Protein ID |
Q99PI8 |
Species |
Mouse |
Exact Sequence |
Cys27-Ser447 |
| Molecular Weight | The protein has a predicted MW of 46.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse NOGOR is greater than 95% as determined by SEC-HPLC. |
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Mouse NOGOR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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