Mouse PILRA Protein (PRA-MM101)
Catalog: PRA-MM101
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| Product Description | Recombinant Mouse PILRA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Val197. |
Product Background |
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD. |
Product Category |
Recombinant Protein |
Target |
PILRA |
Gene/Protein ID |
Q2YFS3-1 |
Species |
Mouse |
Exact Sequence |
Glu32-Val197 |
| Molecular Weight | The protein has a predicted MW of 19.71 kDa. Due to glycosylation, the protein migrates to 43-60 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse PILRA is greater than 95% as determined by SEC-HPLC. |
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Mouse PILRA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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