Biotinylated Human MRGPRX2 Nanodisc (MR2-HM10XN)

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test).
Recomended Products: Biotinylated Nanodisc Control (CON-HM1NB)
Amino Acid Range: Met1-Val330

Catalog #MR2-HM10XN

Price

$2,165.90

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Biotinylated Human MRGPRX2 Nanodisc (MR2-HM10XN) Summary

Product Description	Recombinant Biotinylated Human MRGPRX2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val330.
Product Background	As receptor for multiple drugs, MRGPRX2 is crucial to drug-induced hypersensitivity. However, not only drugs, but also endogenous mediators like neuropeptides and host defense peptides activate MRGPRX2, suggesting its broad impact in cutaneous pathophysiology.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	MRGPRX2
Synonyms	MRGX2
Accession	Q96LB1
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Val330
Molecular Weight	The protein has a predicted MW of 50.1 kDa.
Activity	Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test).
Product Tag	C-His
Fluorophore	Biotin-labeled
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test).
	Loaded Biotinylated Human MRGPRX2 Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-MRGPRX2 Antibody, mFc Tag with an affinity constant of 0.25 nM as determined in BLI assay .

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