Human OSCAR Protein (OAR-HM201)
Human OSCAR Protein (OAR-HM201)
  • Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human OSCAR, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-OSCAR Antibody, hFc Tag with the EC50 42.0ng/ml determined by ELISA.
  • Amino Acid Range: Asp19-Ser229
Catalog #OAR-HM201
Regular price $330.00
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Size
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Human OSCAR Protein (OAR-HM201) Summary

Product Description

Recombinant Human OSCAR Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Asp19-Ser229.

Product Background

Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human OSCAR Protein (OAR-HM201) Specifications/Details

Protein
OSCAR
Synonyms
mOSCAR; OSCAR; PIGR3; PIgR-3; Poly-Ig receptor 3; MGC33613
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Asp19-Ser229
Molecular Weight
The protein has a predicted MW of 49.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human OSCAR, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-OSCAR Antibody, hFc Tag with the EC50 42.0ng/ml determined by ELISA.
Product Tag
C-hFc (IgG1)

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human OSCAR, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-OSCAR Antibody, hFc Tag with the EC50 42.0ng/ml determined by ELISA. Immobilized Human OSCAR, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-OSCAR Antibody, hFc Tag with the EC50 42.0ng/ml determined by ELISA.
Human OSCAR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human OSCAR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human OSCAR is greater than 95% as determined by SEC-HPLC. The purity of Human OSCAR is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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