SEC-HPLC chromatogram of a protein sample showing a main peak eluting at approximately 9.64 minutes, indicating sample purity and molecular size distribution.
Canine OSMR beta-Protein (OSM-DM101)
SEC-HPLC chromatogram of a protein sample showing a main peak eluting at approximately 9.64 minutes, indicating sample purity and molecular size distribution.
Canine OSMR beta-Protein (OSM-DM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu28-Pro735
Catalog #OSM-DM101
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Size
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Canine OSMR beta-Protein (OSM-DM101) Summary

Product Description

 Recombinant Canine OSMR beta-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Pro735.

Product Background

 OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery/Others

Canine OSMR beta-Protein (OSM-DM101) Specifications/Details

Protein
 OSMR beta
Synonyms
 IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ;IL-31R subunit β; IL-31R-β; OSMR β
Accession
Species
 Canine
Biotinylated
 no
Amino Acid Range
 Glu28-Pro735
Molecular Weight
 The protein has a predicted MW of 81.73 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Canine OSMR beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Canine OSMR beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine OSMR beta is greater than 95% as determined by SEC-HPLC. The purity of Canine OSMR beta is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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