• Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu30-Ala369
Catalog #SRP-HM40BB
Price
Regular price $57750
Regular price Sale price $57750
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Size
Avantor VWR Fisher Scientific

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Biotinylated Human SIRP Beta/CD172b Protein (SRP-HM40BB) Summary

Product Description

 Recombinant Biotinylated Human SIRP Beta/CD172b Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Ala369.

Product Background

 SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.

Biotinylated Human SIRP Beta/CD172b Protein (SRP-HM40BB) Specifications/Details

Protein
 SIRP Beta/CD172b
Synonyms
 SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a;SIRP-β-1 isoform 3; SIRP-β;SIRP-b-1 isoform 3; SIRP-b1 isoform 3; SIRP-b
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Glu30-Ala369
Molecular Weight
 The protein has a predicted MW of 40 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi
Fluorophore
 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human SIRP Beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human SIRP Beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human SIRP Beta is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human SIRP Beta is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...