Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM4V3B)
Catalog: ITG-MM4V3B
Order now get it on
| Product Description | Recombinant Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail. |
Product Background |
ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
Product Category |
Recombinant Protein |
Target |
Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer |
Gene/Protein ID |
P43406(ITGAV)&O54890(ITGB3) |
Species |
Mouse |
Exact Sequence |
Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail |
| Molecular Weight | The protein has a predicted MW of 108.77 kDa(ITGAV)&80.84 kDa(ITGB3). Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human Vitronectin, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 3.2ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Human Vitronectin, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 3.2ug/ml determined by ELISA. |
|
|
Biotinylated Mouse ITGAV&ITGB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
You may also be interested in
View more associated products