Cynomolgus LY6G6D Protein (LYD-CM26D)

Express System: HEK293
Product Tag: N-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus LY6G6D, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Asn20-Ser104

Catalog: LYD-CM26D

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Product Description	Recombinant Cynomolgus LY6G6D Protein is expressed from HEK293 with hFc tag at the N-terminus.It contains Asn20-Ser104.
Product Background	LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
Product Category	Recombinant Protein

Target	LY6G6D
Gene/Protein ID	XP_045246087.1
Species	Cynomolgus
Exact Sequence	Asn20-Ser104
Molecular Weight	The protein has a predicted MW of 34.65 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus LY6G6D, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus LY6G6D, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA.
	The purity of Cynomolgus LY6G6D is greater than 95% as determined by SEC-HPLC.
	Cynomolgus LY6G6D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.