Cynomolgus MERTK/Mer Protein (MEK-CM101)
Catalog: MEK-CM101
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Product Description | Recombinant Cynomolgus MERTK/Mer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala23-Ile507. |
Product Background |
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. |
Product Category |
Recombinant Protein |
Target |
MERTK/Mer |
Gene/Protein ID |
XP_005575320.2 |
Species |
Cynomolgus |
Exact Sequence |
Ala23-Ile507 |
Molecular Weight | The protein has a predicted MW of 53.85 kDa. Due to glycosylation, the protein migrates to 58-115 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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