Cynomolgus/Rhesus macaque Her3 Protein (HER-CM403)
Catalog: HER-CM403
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| Product Description | Recombinant Cynomolgus/Rhesus macaque Her3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-His641. |
Product Background |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
Product Category |
Recombinant Protein |
Target |
Her3 |
Gene/Protein ID |
XP_005571238.1/G7N7B1 |
Species |
Cynomolgus/Rhesus macaque |
Exact Sequence |
Ser20-His641 |
| Molecular Weight | The protein has a predicted MW of 69.54 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA. |
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Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 0.12ug/ml determined by ELISA (QC Test). |
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The purity of Cynomolgus/Rhesus macaque Her3 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus/Rhesus macaque Her3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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