Name: Mouse Clusterin Protein (CLN-MM101)
Brand: KactusBio
SKU: CLN-MM101-100UG
Price: 297.0 USD
Availability: InStock

Catalog #CLN-MM101

Size

100UG

500UG

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Mouse Clusterin Protein (CLN-MM101) Summary

Product Description	Recombinant Mouse Clusterin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Glu448.
Product Background	Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse Clusterin Protein (CLN-MM101) Specifications/Details

Protein	Clusterin
Synonyms	Clusterin; Apo-J; Clustrin; SGP-2; Msgp-2; CLU; AAG4; APOJ; CLI; KUB1; SP-40; TRPM2; CLI; KUB1;
Accession	Q06890
Species	Mouse
Biotinylated	no
Amino Acid Range	Glu22-Glu448
Molecular Weight	The protein has a predicted MW of 50.4 kDa. Due to autocatalytic cleavage, the protein migrates to 35-40 kDa and 43-50 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse Clusterin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Clusterin is greater than 95% as determined by SEC-HPLC.