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Mouse EDA2R Protein (EDA-MM22R) Summary
Product Description |
Recombinant Mouse EDA2R Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Met1-Thr138. |
Product Background |
EDA2R is a member of the large family of tumor necrosis factor receptor (TNFR). Previous studies suggested that EDA2R expression might be increased in the kidneys of diabetic mice. High glucose increases EDA2R expression in kidney cells and that EDA2R induces podocyte apoptosis and dedifferentiation in high glucose milieu partially through enhanced ROS generation. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse EDA2R Protein (EDA-MM22R) Specifications/Details
Protein |
EDA2R |
Synonyms |
X-linked ectodysplasin-A2 receptor; EDA-A2 receptor; EDA-A2; Tnfrsf27; Xedar |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Met1-Thr138 |
Molecular Weight |
The protein has a predicted MW of 42.15 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Mouse EDA2R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Mouse EDA2R is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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