Mouse GP1BB Protein (GP1-MM2BB)

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Pro27-Cys147

Catalog #GP1-MM2BB

Price

$330⁰⁰

Size

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Mouse GP1BB Protein (GP1-MM2BB) Summary

Product Description

Recombinant Mouse GP1BB Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Pro27-Cys147.

Product Background

The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superfamily of proteins containing conserved leucine-rich motifs. Association between GP Ib alpha and GP Ib beta was demonstrated biochemically on immunoblots of detergent lysates of CHO alpha beta cells; electrophoresis under nonreducing conditions revealed the two subunits to be covalently linked through a disulfide bond.

Mouse GP1BB Protein (GP1-MM2BB) Specifications/Details

Protein	GP1BB
Synonyms	GP-Ib beta; GPIb-beta; GPIbB; Gp1bb; BDPLT1; BS; CD42c; GP1BB; GPIbb; GPIbbeta;GP-Ib β; GPIb-β; GPIbβ;GP-Ib b; GPIb-b; GPIb beta
Accession	P56400
Species	Mouse
Biotinylated	no
Amino Acid Range	Pro27-Cys147
Molecular Weight	The protein has a predicted MW of 39.5 kDa. Due to glycosylation, the protein migrates to 46-50 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Mouse GP1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse GP1BB is greater than 95% as determined by SEC-HPLC.