• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ile27-Pro250
Catalog #HBP-HM101
Price
Regular price $19800
Regular price Sale price $19800
/
Size
Avantor VWR Fisher Scientific

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Human Azurocidin/CAP37/AZU1/HBP Protein (HBP-HM101) Summary

Product Description

 Recombinant Human Azurocidin/CAP37/AZU1 /HBP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile27-Pro250.

Product Background

 Heparin-binding protein (HBP), also known as cationic antimicrobial protein 37 (CAP37) and Azurocidin, is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3). This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

Human Azurocidin/CAP37/AZU1/HBP Protein (HBP-HM101) Specifications/Details

Protein
 Azurocidin/CAP37/AZU1/HBP
Synonyms
 CAP37; AZU; AZU1; Azurocidin; HBP; AZAMP; HUMAZUR; NAZC; azurocidin 1
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ile27-Pro250
Molecular Weight
 The protein has a predicted MW of 25.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in 20mM PB, 500mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human Azurocidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Azurocidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human Azurocidin is greater than 95% as determined by SEC-HPLC. The purity of Human Azurocidin is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...